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Structure of 121588-79-2
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trans-4-Methoxycyclohexan-1-amine features a stable trans-diaxial arrangement that imparts conformational rigidity, enhancing its utility in stereocontrolled synthesis. The methoxy group provides polar solubility and modulates electronic effects, while the primary amine serves as a robust coupling handle for diversification. This scaffold enables efficient access to bioactive heterocycles and functional materials under standard conditions.
trans-4-Methoxycyclohexan-1-amine serves as a versatile chiral building block in medicinal chemistry, offering a rigid, conformationally defined scaffold with orthogonal functional handles. The amine group enables facile derivatization via acylation, alkylation, or reductive amination, while the methoxy substituent provides steric and electronic modulation. Its bench-stable nature and compatibility with standard purification protocols make it well-suited for iterative synthesis workflows and target-oriented library development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: