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CS-W001157 4
Total: USD 88.00

(R)-Morpholine-2-carboxylic acid

  • CAS No. 1212396-52-5

  • Cat. No. CS-0102851
  • Purity≥97%
  • MDL No.MFCD11052514

*For research and further manufacturing use only, not for direct human use.

(R)-Morpholine-2-carboxylic acid|CS-0102851

Structure of 1212396-52-5

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General Information

  • CAS No. 1212396-52-5
  • Cat. No. CS-0102851
  • Purity ≥97%
  • MDL No. MFCD11052514
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉NO₃
  • Molecular Weight 131.13
  • Synonym(s) (R)-Morpholine-2-carboxylicacid
  • SMILES O=C([C@H]1CNCCO1)O

Description

(R)-Morpholine-2-carboxylic acid is a chiral building block featuring a rigid, electron-rich morpholine ring fused to a carboxylic acid at the 2-position. This configuration enables high stereoselectivity in peptide synthesis and bioactive molecule construction. The compound exhibits excellent solubility in polar solvents and stability under standard bench conditions, facilitating integration into diverse synthetic workflows.

Application

(R)-Morpholine-2-carboxylic acid serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through established coupling and cyclization protocols. Its well-defined stereochemistry and stability under standard reaction conditions facilitate reliable incorporation into peptidomimetics and heterocyclic scaffolds. The carboxylic acid functionality supports direct derivatization or activation for amide bond formation, while the morpholine ring provides favorable solubility and metabolic profile attributes.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   -0.9406
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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