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CS-W001157 4
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(R)-Morpholine-3-carboxylic acid

  • CAS No. 106825-81-4

  • Cat. No. CS-0053321
  • Purity≥97%
  • MDL No.MFCD03426306

*For research and further manufacturing use only, not for direct human use.

(R)-Morpholine-3-carboxylic acid|CS-0053321

Structure of 106825-81-4

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General Information

  • CAS No. 106825-81-4
  • Cat. No. CS-0053321
  • Purity ≥97%
  • MDL No. MFCD03426306
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉NO₃
  • Molecular Weight 131.13
  • Synonym(s) 3-Morpholinecarboxylic acid, (3R)
  • SMILES OC(=O)[C@H]1COCCN1

Description

(R)-Morpholine-3-carboxylic acid features a chiral morpholine core with a carboxylic acid functional group at the 3-position, enabling direct incorporation into peptidomimetics and bioactive scaffolds. The stereochemistry enhances binding selectivity in target-directed synthesis, while its solubility profile supports efficient coupling under standard conditions.

Application

(R)-Morpholine-3-carboxylic acid serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and peptide mimetics. Its well-defined stereochemistry and stability under standard reaction conditions facilitate efficient derivatization via amide coupling, esterification, and reduction. The molecule exhibits excellent functional group tolerance and is readily purified by recrystallization or chromatography, making it ideal for scalable synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P304+P341-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   -0.9406
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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