Lot numbers can be found on the outside label of a product:
(R)-4-(tert-butoxycarbonyl)morpholine-3-carboxylic acid
-
CAS No. 869681-70-9
- Cat. No. CS-W019728
- Purity≥97%
- MDL No.MFCD04114909
*For research and further manufacturing use only, not for direct human use.
Structure of 869681-70-9
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 869681-70-9
- Cat. No. CS-W019728
- Purity ≥97%
- MDL No. MFCD04114909
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₀H₁₇NO₅
- Molecular Weight 231.25
- Synonym(s) (3R)-4-(tert-butoxycarbonyl)morpholine-3-carboxylic acid
- SMILES O=C(OC(C)(C)C)N1[C@H](COCC1)C(O)=O
Description
(R)-4-(tert-butoxycarbonyl)morpholine-3-carboxylic acid features a stereodefined morpholine core with a bench-stable tert-butyl ester protecting group, enabling straightforward functionalization in peptide synthesis and medicinal chemistry. The carboxylic acid moiety facilitates coupling reactions under standard conditions, while the cyclic amine scaffold provides conformational rigidity for targeted bioactive molecule design.
Application
(R)-4-(tert-butoxycarbonyl)morpholine-3-carboxylic acid serves as a versatile chiral building block for the synthesis of bioactive heterocycles and peptide mimetics. The Boc-protected morpholine-3-carboxylic acid moiety offers excellent bench stability, compatibility with standard coupling conditions, and facilitates orthogonal deprotection during multi-step syntheses. Its defined stereochemistry enables reliable access to enantioselective scaffolds relevant to medicinal chemistry campaigns.
Synthesis
-
Route1
-
1207428-21-4 - ~%
-
In-stock
869681-70-9
References
-
WO2010/15626 A1, ; Page/Page column 22-23 ; WO 2010/015626 A1
-
-
Route2
-
In-stock
714971-28-5 - ~85%
-
In-stock
869681-70-9
References
-
Tetrahedron Asymmetry, , vol. 17, # 3 p. 388 - 401
-
-
Route3
-
In-stock
211053-50-8 - ~%
-
In-stock
869681-70-9
References
-
Tetrahedron Asymmetry, , vol. 17, # 3 p. 388 - 401
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 76.07
- LogP 0.7069
- H_Acceptors 4
- H_Donors 1
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 869681-70-9 sigma869681-70-9 manufacturer869681-70-9 price869681-70-9 structure869681-70-9 SDSbuy 869681-70-9869681-70-9 supplier869681-70-9 uses869681-70-9 molecular weightprice of 869681-70-9869681-70-9 chemical name formula of 869681-70-9