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CS-W001157 4
Total: USD 88.00

4-Boc-3-Morpholinecarboxylic acid

  • CAS No. 212650-43-6

  • Cat. No. CS-M0709
  • Purity≥97%
  • MDL No.MFCD02683057

*For research and further manufacturing use only, not for direct human use.

4-Boc-3-Morpholinecarboxylic acid|CS-M0709

Structure of 212650-43-6

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General Information

  • CAS No. 212650-43-6
  • Cat. No. CS-M0709
  • Purity ≥97%
  • MDL No. MFCD02683057
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₇NO₅
  • Molecular Weight 231.25
  • Synonym(s) N-Boc-morpholine-3-carboxylic acid
  • SMILES O=C(OC(C)(C)C)N1C(COCC1)C(O)=O

Description

4-Boc-3-Morpholinecarboxylic acid features a protected morpholine ring with a tert-butoxycarbonyl group at the C4 position, enabling stable incorporation into peptide and small-molecule syntheses. The Boc moiety provides orthogonal protection, facilitating selective deprotection under mild acidic conditions. This derivative delivers enhanced solubility and reduced nucleophilicity compared to unprotected analogs, streamlining downstream functionalization in complex molecular architectures.

Application

4-Boc-3-morpholinecarboxylic acid serves as a stable, bench-ready morpholine-containing building block for peptide and medicinal chemistry applications. The Boc group provides orthogonal protection for the amine, enabling selective deprotection during synthesis. It functions as a key intermediate in constructing morpholine-based heterocycles and bioactive scaffolds, offering excellent functional group tolerance and compatibility with standard coupling protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   76.07
  • LogP   0.7069
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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