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Structure of 1211589-43-3
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3-Bromo-6-fluoropicolinic acid features a strategically positioned bromo and fluoro substituent on the picolinic acid scaffold, enabling selective functionalization in cross-coupling reactions. This electron-deficient heterocycle delivers high reactivity under palladium catalysis while maintaining bench-stable handling characteristics.
3-Bromo-6-fluoropicolinic acid serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the 3-position via palladium-catalyzed cross-coupling reactions. Its orthogonal halogenation pattern (Br and F) supports sequential transformations and facilitates late-stage diversification in API synthesis. The carboxylic acid group provides a handle for amide formation or ester derivatization, while the molecule exhibits excellent bench stability and compatibility with standard purification methods.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: