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CS-W001157 4
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tert-Butyl 4-(piperidin-4-ylmethyl)piperazine-1-carboxylate

  • CAS No. 1211568-27-2

  • Cat. No. CS-0144186
  • Molecule weight283.42
  • Purity≥98%
  • MDL No.MFCD21145604

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 4-(piperidin-4-ylmethyl)piperazine-1-carboxylate|CS-0144186

Structure of 1211568-27-2

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General Information

  • CAS No. 1211568-27-2
  • Cat. No. CS-0144186
  • Purity ≥98%
  • MDL No. MFCD21145604
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₉N₃O₂
  • Molecular Weight 283.42
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)N1CCN(CC1)CC2CCNCC2

Description

tert-Butyl 4-(piperidin-4-ylmethyl)piperazine-1-carboxylate features a bifunctional piperazine scaffold with a pendant piperidine tether, enabling efficient integration into complex heterocyclic architectures. This bench-stable, moisture-tolerant building block facilitates streamlined synthesis of bioactive amine derivatives and targeted ligands in medicinal chemistry campaigns.

Application

tert-Butyl 4-(piperidin-4-ylmethyl)piperazine-1-carboxylate serves as a versatile bis-heterocyclic building block, enabling efficient construction of complex nitrogen-rich scaffolds. Its piperazine core facilitates diverse functionalization, while the tert-butyl carbamate group offers stability and orthogonal deprotection under mild acidic conditions. The molecule exhibits excellent solubility and bench stability, simplifying purification and integration into multi-step synthetic sequences for medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   44.81
  • LogP   1.5387
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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