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Structure of 1211542-29-8
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3-Bromo-5-fluoro-2-methylpyridine features a trifunctional pyridine core with bromo, fluoro, and methyl substituents positioned for orthogonal reactivity. This electron-deficient heterocycle enables seamless cross-coupling and nucleophilic substitution under standard conditions. The molecule exhibits enhanced stability and solubility in polar aprotic solvents, facilitating integration into complex synthetic sequences.
3-Bromo-5-fluoro-2-methylpyridine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The methyl group provides a site for oxidation or functionalization, while the fluorine and bromine substituents offer tunable electronic effects and synthetic handle diversity. Its bench-stable nature and compatibility with standard reaction conditions facilitate efficient access to substituted heterocyclic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: