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CS-W001157 4
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7-Bromobenzo[d]oxazol-2-amine

  • CAS No. 1211527-07-9

  • Cat. No. CS-0136287
  • Purity≥97%
  • MDL No.MFCD19375775

*For research and further manufacturing use only, not for direct human use.

7-Bromobenzo[d]oxazol-2-amine|CS-0136287

Structure of 1211527-07-9

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General Information

  • CAS No. 1211527-07-9
  • Cat. No. CS-0136287
  • Purity ≥97%
  • MDL No. MFCD19375775
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅BrN₂O
  • Molecular Weight 213.03
  • Synonym(s) 7-bromobenzo[d]oxazol-2(3H)-imine
  • SMILES NC1=NC2=CC=CC(Br)=C2O1

Description

7-Bromobenzo[d]oxazol-2-amine features a brominated oxazole core with an amine at the 2-position, enabling direct functionalization in cross-coupling and bioconjugation. This bench-stable heterocycle integrates readily into pharmaceutical scaffolds and fluorescent probes due to its electron-deficient character and compatibility with palladium-catalyzed transformations under standard conditions.

Application

7-Bromobenzo[d]oxazol-2-amine serves as a versatile building block for the synthesis of functionalized heterocycles and pharmaceutical intermediates. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, while the amine group facilitates derivatization via acylation, alkylation, or cyclization. The compound exhibits good bench stability and is compatible with standard purification protocols, making it well-suited for iterative synthetic strategies in medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.05
  • LogP   2.1725
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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