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CS-W001157 4
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Fmoc-Dab-OH

  • CAS No. 161420-87-7

  • Cat. No. CS-W006453
  • Purity≥97%
  • MDL No.MFCD00237017

*For research and further manufacturing use only, not for direct human use.

Fmoc-Dab-OH|CS-W006453

Structure of 161420-87-7

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General Information

  • CAS No. 161420-87-7
  • Cat. No. CS-W006453
  • Purity ≥97%
  • MDL No. MFCD00237017
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₂₀N₂O₄
  • Molecular Weight 340.37
  • Synonym(s) (S)-2-(Fmoc-amino)-4-aminobutanoic Acid
  • SMILES O=C([C@H](CCN)NC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)O

Description

Fmoc-Dab-OH is a key building block for solid-phase peptide synthesis, featuring a side-chain primary amine that enables efficient conjugation and chain extension. The fluorenylmethoxy carbonyl (Fmoc) group provides orthogonal protection, ensuring selective deprotection under mild basic conditions. This derivative supports rapid assembly of complex peptides with high fidelity and minimal epimerization.

Application

Fmoc-Dab-OH serves as a key bifunctional building block in peptide synthesis, enabling the incorporation of side-chain amine functionality for conjugation or branching. The Fmoc group provides orthogonal protection compatible with standard solid-phase workflows, while the free α- and side-chain amines facilitate efficient coupling reactions. Its bench-stable nature and compatibility with diverse coupling reagents make it ideal for constructing complex peptide architectures and peptidomimetics.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   101.65
  • LogP   2.3271
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   6

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