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CS-W001157 4
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tert-Butyl 6,7-dihydro-1H-imidazo[4,5-c]pyridine-5(4H)-carboxylate

  • CAS No. 1202800-68-7

  • Cat. No. CS-W000464
  • Purity≥96%
  • MDL No.MFCD18632673

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 6,7-dihydro-1H-imidazo[4,5-c]pyridine-5(4H)-carboxylate|CS-W000464

Structure of 1202800-68-7

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General Information

  • CAS No. 1202800-68-7
  • Cat. No. CS-W000464
  • Purity ≥96%
  • MDL No. MFCD18632673
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₇N₃O₂
  • Molecular Weight None
  • Synonym(s) 2-Methyl-2-propanyl 1,4,6,7-tetrahydro-5H-imidazo[4,5-c]pyridine-5-carboxylate
  • SMILES O=C(N1CCC2=C(NC=N2)C1)OC(C)(C)C

Description

tert-Butyl 6,7-dihydro-1H-imidazo[4,5-c]pyridine-5(4H)-carboxylate features a saturated imidazopyridine core with a protected carboxylic acid moiety. This bench-stable scaffold integrates readily into medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds. The tert-butyl ester enhances solubility and stability during synthetic manipulations.

Application

tert-Butyl 6,7-dihydro-1H-imidazo[4,5-c]pyridine-5(4H)-carboxylate serves as a versatile heterocyclic building block for medicinal chemistry and process development. The protected pyridine scaffold exhibits robust bench stability and compatibility with standard coupling reactions, enabling efficient access to imidazopyridine derivatives. Its tert-butyl ester group facilitates straightforward deprotection under mild acidic conditions, supporting rapid analog synthesis. Functions reliably in diverse transformations involving nucleophilic substitution and transition-metal-catalyzed cross-couplings.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   58.22
  • LogP   1.7029
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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