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4,5,6,7-Tetrahydro-3H-imidazo[4,5-c]pyridine dihydrochloride

  • CAS No. 62002-31-7

  • Cat. No. CS-W002483
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4,5,6,7-Tetrahydro-3H-imidazo[4,5-c]pyridine dihydrochloride|CS-W002483

Structure of 62002-31-7

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General Information

  • CAS No. 62002-31-7
  • Cat. No. CS-W002483
  • Purity ≥96%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁Cl₂N₃
  • Molecular Weight 196.08
  • Synonym(s) 4,5,6,7-Tetrahydro-3H-imidazo[4,5-c]pyridine hydrochloride
  • SMILES C1(NC=N2)=C2CCNC1.Cl.Cl

Description

This tetrahydroimidazopyridine dihydrochloride features a rigid, electron-rich heterocyclic core that enhances binding affinity in medicinal chemistry applications. The dihydrochloride salt form improves solubility and stability under standard conditions, enabling reliable use in synthetic transformations and biological screening workflows.

Application

4,5,6,7-Tetrahydro-3H-imidazo[4,5-c]pyridine dihydrochloride serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to imidazopyridine scaffolds prevalent in kinase inhibitors and CNS-active compounds. The dihydrochloride salt enhances solubility and stability in aqueous media, facilitating purification and handling during synthetic workflows. Its well-defined reactivity profile supports direct functionalization at nitrogen positions and compatibility with standard coupling reactions.

Synthesis

  • Route1

    References

    • Russian Journal of Organic Chemistry, , vol. 38, # 3 p. 419 - 423

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.71
  • LogP   0.899
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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