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CS-W001157 4
Total: USD 88.00

3,5-Dibromopyridazine

  • CAS No. 1196155-35-7

  • Cat. No. CS-0067515
  • Purity≥98%
  • MDL No.MFCD13190294

*For research and further manufacturing use only, not for direct human use.

3,5-Dibromopyridazine|CS-0067515

Structure of 1196155-35-7

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General Information

  • CAS No. 1196155-35-7
  • Cat. No. CS-0067515
  • Purity ≥98%
  • MDL No. MFCD13190294
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₂Br₂N₂
  • Molecular Weight 237.88
  • Synonym(s) None
  • SMILES BrC1=CC(Br)=NN=C1

Description

3,5-Dibromopyridazine is a heterocyclic bromide featuring two bromine substituents at the 3 and 5 positions of the pyridazine ring. This electron-deficient scaffold enables direct functionalization in cross-coupling reactions, serving as a key intermediate in medicinal chemistry. The molecule exhibits enhanced reactivity due to the combined electronic effects of adjacent halogens, facilitating efficient C–C and C–heteroatom bond formation under palladium catalysis.

Application

3,5-Dibromopyridazine serves as a versatile building block in heterocyclic synthesis, enabling efficient palladium-catalyzed cross-coupling reactions due to its orthogonal reactivity and bench-stable bromide functionalities. The molecule facilitates the construction of complex pyridazine-based scaffolds common in pharmaceutical intermediates, with predictable regioselectivity and compatibility across standard coupling conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   2.0016
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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