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CS-W001157 4
Total: USD 88.00

3,4,5-Tribromopyridazine

  • CAS No. 1822854-37-4

  • Cat. No. CS-0132817
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3,4,5-Tribromopyridazine|CS-0132817

Structure of 1822854-37-4

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General Information

  • CAS No. 1822854-37-4
  • Cat. No. CS-0132817
  • Purity ≥98%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄HBr₃N₂
  • Molecular Weight 316.78
  • Synonym(s) None
  • SMILES BrC1=C(Br)C(Br)=NN=C1

Description

3,4,5-Tribromopyridazine is a highly brominated heterocyclic scaffold featuring three bromine substituents at the 3-, 4-, and 5-positions of the pyridazine ring. This configuration imparts strong electron-withdrawing character and enhances reactivity in cross-coupling processes. The molecule exhibits bench-stable handling properties and serves as a key building block for advanced materials and pharmaceutical intermediates requiring dense halogenation.

Application

3,4,5-Tribromopyridazine serves as a versatile building block for the synthesis of brominated heterocyclic scaffolds, enabling efficient late-stage functionalization in medicinal chemistry and materials science. Its three adjacent bromine substituents facilitate sequential cross-coupling reactions, offering high regioselectivity and compatibility with Pd-catalyzed transformations. The compound exhibits excellent bench stability and is readily purified by column chromatography, making it ideal for scalable synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   25.78
  • LogP   2.7641
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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