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CS-W001157 4
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Ethyl 2,4-dihydroxy-1,8-naphthyridine-3-carboxylate

  • CAS No. 1186189-28-5

  • Cat. No. CS-0338929
  • Molecule weight234.21
  • Purity95+%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Ethyl 2,4-dihydroxy-1,8-naphthyridine-3-carboxylate|CS-0338929

Structure of 1186189-28-5

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General Information

  • CAS No. 1186189-28-5
  • Cat. No. CS-0338929
  • Purity 95+%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₀N₂O₄
  • Molecular Weight 234.21
  • Synonym(s) Ethyl 4-hydroxy-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylate
  • SMILES CCOC(=O)C1=C(C2=C(N=CC=C2)N=C1O)O

Synthesis

  • Route1

    References

    • Manera, Clementina; Saccomanni, Giuseppe; Malfitano, Anna Maria; Bertini, Simone; Castelli, Francesca; Laezza, Chiara; Ligresti, Alessia; Lucchesi, Valentina; Tuccinardi, Tiziano; Rizzolio, Flavio; Bifulco, Maurizio; Di Marzo, Vincenzo; Giordano, Antonio; MacChia, Marco; Martinelli, Adriano European Journal of Medicinal Chemistry, 2012 , vol. 52, p. 284 - 294
  • Route2
    • 2-methyl-4H-pyrido[2,3-d][1,3]oxazin-4-one|CS-0664222
      3809-93-6
    • null|null
      105-53-3
    • ~49%
    • Ethyl 2,4-dihydroxy-1,8-naphthyridine-3-carboxylate|CS-0338929
      1186189-28-5

    References

    • Prousis, Kyriakos C.; Tzani, Andromachi; Avlonitis, Nicolaos; Calogeropoulou, Theodora; Detsi, Anastasia Journal of Heterocyclic Chemistry, 2013 , vol. 50, # 6 p. 1313 - 1321
  • Route3

    References

    • Journal of Heterocyclic Chemistry, , vol. 50, # 6 p. 1313 - 1321

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   92.54
  • LogP   1.2177
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   2

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