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Structure of 1185121-45-2
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This pyrrolidine derivative features a trifluoromethoxy-substituted phenyl group, delivering enhanced lipophilicity and metabolic stability. The hydrochloride salt form ensures excellent solubility and crystalline purity, enabling reliable performance in medicinal chemistry applications.
2-(4-(Trifluoromethoxy)phenyl)pyrrolidine hydrochloride serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard amine functionalization. The trifluoromethoxy group imparts enhanced metabolic stability and lipophilicity, while the pyrrolidine ring provides a rigid, conformationally restricted framework suitable for target engagement. Its hydrochloride salt form ensures excellent bench stability, ease of handling, and straightforward purification—ideal for high-throughput synthesis and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: