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CS-W001157 4
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Methyl 1-(aminomethyl)cyclobutanecarboxylate hydrochloride

  • CAS No. 1172902-07-6

  • Cat. No. CS-W003743
  • Purity≥98%
  • MDL No.MFCD10758084

*For research and further manufacturing use only, not for direct human use.

Methyl 1-(aminomethyl)cyclobutanecarboxylate hydrochloride|CS-W003743

Structure of 1172902-07-6

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General Information

  • CAS No. 1172902-07-6
  • Cat. No. CS-W003743
  • Purity ≥98%
  • MDL No. MFCD10758084
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄ClNO₂
  • Molecular Weight 179.65
  • Synonym(s) Methyl 1-(aminomethyl)cyclobutanecarboxylatehydrochloride
  • SMILES NCC1(CCC1)C(=O)OC.Cl

Description

Methyl 1-(aminomethyl)cyclobutanecarboxylate hydrochloride features a rigid cyclobutane core with a pendant aminomethyl group, enabling efficient incorporation into bioactive scaffolds. The protonated amine enhances solubility and facilitates salt formation, improving handling and stability under standard conditions. This derivative serves as a key building block in medicinal chemistry for targeted peptide and small-molecule synthesis.

Application

Methyl 1-(aminomethyl)cyclobutanecarboxylate hydrochloride serves as a versatile building block for cyclobutane-containing bioactive molecules. The protected amine and ester functionalities enable orthogonal transformations, facilitating late-stage diversification in medicinal chemistry. Bench-stable and readily purified, it functions effectively in nucleophilic substitution, reductive amination, and coupling reactions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   0.7102
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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