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CS-W001157 4
Total: USD 88.00

(1-(Aminomethyl)cyclobutyl)methanol

  • CAS No. 2041-56-7

  • Cat. No. CS-W021055
  • Purity≥95%
  • MDL No.MFCD09864389

*For research and further manufacturing use only, not for direct human use.

(1-(Aminomethyl)cyclobutyl)methanol|CS-W021055

Structure of 2041-56-7

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General Information

  • CAS No. 2041-56-7
  • Cat. No. CS-W021055
  • Purity ≥95%
  • MDL No. MFCD09864389
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃NO
  • Molecular Weight 115.17
  • Synonym(s) [1-(Aminomethyl)cyclobutyl]methanol
  • SMILES OCC1(CN)CCC1

Description

This aminomethylcyclobutylmethanol features a cyclobutyl ring bearing a pendant methanol and aminomethyl group, offering a rigid, sterically constrained scaffold. The bifunctional motif enables direct incorporation into peptide mimetics or bioactive compounds, where the primary amine facilitates conjugation and the hydroxyl supports hydrogen bonding. Bench-stable and moisture-tolerant, it streamlines synthetic access to cyclic amine derivatives in medicinal chemistry workflows.

Application

(1-(Aminomethyl)cyclobutyl)methanol serves as a versatile building block in medicinal chemistry, enabling the construction of cyclobutane-containing scaffolds with defined stereochemistry. The primary amine and hydroxyl groups offer orthogonal functionalization potential, facilitating coupling reactions, derivatization, or incorporation into bioactive molecules. Its bench-stable nature and compatibility with standard synthetic protocols make it well-suited for iterative synthesis and process development.

Synthesis

  • Route1

    References

    • Journal of medicinal chemistry, , vol. 15, # 10 p. 1003 - 1006

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H314-H227
Precautionary Statements : P210-P280-P370+P378-P403+P235-P260-P264-P270-P280-P301+P310-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   0.1077
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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