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(S)-1-(P-tolyl)propan-1-amine hydrochloride

  • CAS No. 1168139-46-5

  • Cat. No. CS-0372159
  • Molecule weight185.69
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-1-(P-tolyl)propan-1-amine hydrochloride|CS-0372159

Structure of 1168139-46-5

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General Information

  • CAS No. 1168139-46-5
  • Cat. No. CS-0372159
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₆ClN
  • Molecular Weight 185.69
  • Synonym(s) (S)-1-P-TOLYLPROPAN-1-AMINE-HCl
  • SMILES CC[C@@H](C1=CC=C(C=C1)C)N.Cl

Description

(S)-1-(p-Tolyl)propan-1-amine hydrochloride features a chiral benzylic center with a para-methylphenyl group, delivering high enantiomeric purity for asymmetric synthesis. This bench-stable, moisture-tolerant amine serves as a key chiral auxiliary in catalytic transformations and pharmaceutical intermediates, enabling precise stereocontrol under standard conditions.

Application

(S)-1-(p-Tolyl)propan-1-amine hydrochloride serves as a chiral building block for asymmetric synthesis, offering well-documented enantioselective functionality in medicinal chemistry and catalytic applications. The benzylamine scaffold provides excellent functional group tolerance and bench stability, enabling straightforward derivatization via alkylation, acylation, or reductive amination. Its crystalline hydrochloride salt form ensures ease of handling, purification, and storage, making it a practical choice for scalable synthesis of API intermediates and ligands.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.82662
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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