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CS-W001157 4
Total: USD 88.00

(5-Methyl-1H-pyrazol-3-yl)boronic acid

  • CAS No. 1163248-54-1

  • Cat. No. CS-W018579
  • Purity≥95%
  • MDL No.MFCD14636621

*For research and further manufacturing use only, not for direct human use.

(5-Methyl-1H-pyrazol-3-yl)boronic acid|CS-W018579

Structure of 1163248-54-1

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General Information

  • CAS No. 1163248-54-1
  • Cat. No. CS-W018579
  • Purity ≥95%
  • MDL No. MFCD14636621
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇BN₂O₂
  • Molecular Weight 125.92
  • Synonym(s) beta-(5-Methyl-1H-pyrazol-3-yl)boronic acid
  • SMILES CC1=CC(=NN1)B(O)O

Description

This boronate moiety integrates readily into Suzuki-Miyaura cross-coupling reactions, delivering functionalized pyrazole derivatives with high efficiency. The methyl group enhances solubility and stability under standard conditions, enabling straightforward incorporation into complex molecular architectures.

Application

(5-Methyl-1H-pyrazol-3-yl)boronic acid serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. Its pyrazole core offers enhanced functional group tolerance and improved solubility in polar solvents, facilitating efficient coupling with aryl and heteroaryl halides. The methyl substituent provides modest steric and electronic modulation, enabling predictable reactivity in the construction of biologically relevant heterocyclic scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   69.14
  • LogP   -1.60208
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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