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Structure of 116293-90-4
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6-Fluoroquinoline-3-carboxylic acid features a fluorine atom at the C6 position of the quinoline core, enhancing electron-withdrawing character and metabolic stability. The carboxylic acid group enables direct coupling reactions and facilitates solubility in polar solvents. This scaffold serves as a key building block in medicinal chemistry for kinase inhibitors and fluorescent probes.
6-Fluoroquinoline-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into bioactive scaffolds via standard coupling reactions. Its ortho-fluorine facilitates nucleophilic aromatic substitution, while the carboxylic acid group supports amide, ester, and heterocycle formation. The compound exhibits excellent bench stability and purification compatibility, making it well-suited for iterative synthesis campaigns and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: