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CS-W001157 4
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3-(tert-Butyldimethylsilyloxy)propan-1-amine

  • CAS No. 115306-75-7

  • Cat. No. CS-0139636
  • Purity≥95%
  • MDL No.MFCD18206137

*For research and further manufacturing use only, not for direct human use.

3-(tert-Butyldimethylsilyloxy)propan-1-amine|CS-0139636

Structure of 115306-75-7

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General Information

  • CAS No. 115306-75-7
  • Cat. No. CS-0139636
  • Purity ≥95%
  • MDL No. MFCD18206137
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₂₃NOSi
  • Molecular Weight 189.37
  • Synonym(s) None
  • SMILES O(CCCN)[Si](C)(C)C(C)(C)C

Description

3-(tert-Butyldimethylsilyloxy)propan-1-amine features a silyl-protected hydroxyl group paired with a primary amine, enabling selective functionalization in complex molecule synthesis. This bench-stable derivative facilitates orthogonal protection strategies in organic and peptide chemistry workflows.

Application

3-(tert-Butyldimethylsilyloxy)propan-1-amine serves as a versatile silyl-protected amine building block, enabling stable storage and selective deprotection in multi-step syntheses. Its tert-butyldimethylsilyl (TBS) ether group provides excellent bench stability and orthogonal compatibility with common functional groups. The molecule facilitates efficient incorporation into complex scaffolds via standard coupling reactions, particularly useful in the synthesis of peptide analogs and bioactive heterocycles where controlled reactivity and purification ease are critical.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   2.357
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   4

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