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CS-W001157 4
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4-((tert-Butyldimethylsilyl)oxy)butan-1-amine

  • CAS No. 245660-15-5

  • Cat. No. CS-0435633
  • Purity≥96%
  • MDL No.MFCD18206129

*For research and further manufacturing use only, not for direct human use.

4-((tert-Butyldimethylsilyl)oxy)butan-1-amine|CS-0435633

Structure of 245660-15-5

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General Information

  • CAS No. 245660-15-5
  • Cat. No. CS-0435633
  • Purity ≥96%
  • MDL No. MFCD18206129
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₅NOSi
  • Molecular Weight 203.40
  • Synonym(s) None
  • SMILES O(CCCCN)[Si](C)(C)C(C)(C)C

Description

This silyl-protected amine features a tert-butyldimethylsilyl group that stabilizes the primary amine functionality under basic conditions. The aliphatic chain provides flexible spacing, enabling use in sequential synthesis and protecting group strategies. This derivative offers enhanced solubility and stability during multi-step transformations.

Application

4-((tert-Butyldimethylsilyl)oxy)butan-1-amine serves as a stable, bench-ready protecting group for primary alcohols and amines, enabling orthogonal functionalization in complex molecule synthesis. Its silyl ether moiety facilitates selective deprotection under mild acidic conditions, while the terminal amine supports further derivatization. This compound functions effectively in multi-step sequences requiring precise control over reactivity and stability.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319
Precautionary Statements : P210-P264-P280-P302+P352-P362+P364-P370+P378-P403-P501

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   2.7471
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   5

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