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(2S)-2-[(tert-Butoxycarbonyl)amino]-3-(3-fluorophenyl)propionic acid

  • CAS No. 114873-01-7

  • Cat. No. CS-0011430
  • Purity≥95%
  • MDL No.MFCD00672522

*For research and further manufacturing use only, not for direct human use.

(2S)-2-[(tert-Butoxycarbonyl)amino]-3-(3-fluorophenyl)propionic acid|CS-0011430

Structure of 114873-01-7

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General Information

  • CAS No. 114873-01-7
  • Cat. No. CS-0011430
  • Purity ≥95%
  • MDL No. MFCD00672522
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₈FNO₄
  • Molecular Weight 283.30
  • Synonym(s) (S)-2-[(tert-Butoxycarbonyl)amino]-3-(3-fluorophenyl)propionic acid; tert-Butoxycarbonyl-L-3-fluorophenylalanine
  • SMILES FC1=CC(C[C@H](NC(OC(C)(C)C)=O)C(O)=O)=CC=C1

Synthesis

  • Route1

    References

    • PFIZER INC. Patent: WO2005/26114 A1, 2005 ; Location in patent: Page/Page column 102 ;
  • Route2

    References

    • Maeda; Kawasaki; Watanabe; Kaneto Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 3 p. 826 - 828

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   2.3461
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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