Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

tert-Butyl octahydro-1H-pyrrolo[3,2-c]pyridine-1-carboxylate

  • CAS No. 1147422-00-1

  • Cat. No. CS-0036924
  • Molecule weight226.32
  • Purity≥97%
  • MDL No.MFCD11877862

*For research and further manufacturing use only, not for direct human use.

tert-Butyl octahydro-1H-pyrrolo[3,2-c]pyridine-1-carboxylate|CS-0036924

Structure of 1147422-00-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1147422-00-1
  • Cat. No. CS-0036924
  • Purity ≥97%
  • MDL No. MFCD11877862
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₂N₂O₂
  • Molecular Weight 226.32
  • Synonym(s) tert-butyl octahydro-1H-pyrrolo[3,2-c]pyridine-1-carboxylate, Mixture of diastereomers
  • SMILES CC(C)(C)OC(=O)N1CCC2CNCCC21

Description

tert-Butyl octahydro-1H-pyrrolo[3,2-c]pyridine-1-carboxylate is a bench-stable, moisture-tolerant carbamate protecting group for secondary amines in complex amine synthesis. This saturated heterocyclic scaffold features a sterically hindered tert-butyl ester that facilitates selective deprotection under mild acidic conditions. The molecule integrates cleanly into iterative synthetic sequences and enables efficient access to functionalized pyrrolidine derivatives used in medicinal chemistry and catalytic system design.

Application

tert-Butyl octahydro-1H-pyrrolo[3,2-c]pyridine-1-carboxylate serves as a stable, bench-ready nitrogen heterocycle building block for medicinal and process chemistry. Its tert-butyl carbamate group enables mild deprotection under acidic conditions, while the saturated pyrrolidine-pyridine core provides a rigid, pharmacophoric scaffold. The compound exhibits excellent functional group tolerance and facilitates efficient coupling reactions, making it ideal for constructing complex alkaloid frameworks and targeted API intermediates.

Synthesis

  • Route1
    • tert-Butyl 5-benzyloctahydro-1H-pyrrolo[3,2-c]pyridine-1-carboxylate|CS-0160719
      1147421-99-5
    • ~96%
    • In-stock
      tert-Butyl octahydro-1H-pyrrolo[3,2-c]pyridine-1-carboxylate|CS-0036924
      1147422-00-1

    References

    • F. HOFFMANN-LA ROCHE AG Patent: WO2009/53715 A1, 2009 ; Location in patent: Page/Page column 75 ; WO 2009/053715 A1
  • Route2

    References

    • SUNSHINE LAKE PHARMA CO., LTD.; ZHANG, Jiancun; ZHANG, Yingjun; ZHANG, Weihong; LIU, Bing; ZHANG, Jiquan; LIU, Jinlei; ZHANG, Lu Patent: WO2013/71697 A1, 2013 ; Location in patent: Paragraph 00276 ;
  • Route3

    References

    • WO2013/71697 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   41.57
  • LogP   1.6053
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1147422-00-1 sigma1147422-00-1 manufacturer1147422-00-1 price1147422-00-1 structure1147422-00-1 SDSbuy 1147422-00-11147422-00-1 supplier1147422-00-1 uses1147422-00-1 molecular weightprice of 1147422-00-11147422-00-1 chemical name formula of 1147422-00-1
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label