(S)-2-Methylmorpholine hydrochloride

Name: (S)-2-Methylmorpholine hydrochloride
Brand: ChemScene
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CAS No. 1147108-99-3
Cat. No. CS-W006079
Purity≥98%
MDL No.MFCD11506701

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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(S)-2-Methylmorpholine hydrochloride|CS-W006079

Structure of 1147108-99-3

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Description

(S)-2-Methylmorpholine hydrochloride is a chiral amine salt featuring a stereodefined morpholine ring with a methyl group at the 2-position. This bench-stable, moisture-tolerant compound serves as a selective ligand in asymmetric synthesis and catalysis. The protonated nitrogen enhances solubility in polar solvents while maintaining reactivity in transition-metal-catalyzed transformations.

Application

(S)-2-Methylmorpholine hydrochloride serves as a chiral auxiliary and versatile building block in asymmetric synthesis, enabling stereoselective transformations through its well-defined tertiary amine functionality. The hydrochloride salt enhances bench stability and solubility in polar solvents, facilitating efficient handling and purification. It functions effectively in nucleophilic substitution, metal-catalyzed coupling reactions, and as a scaffold for heterocyclic compound construction, particularly in medicinal chemistry applications requiring controlled stereochemistry.

General Information

CAS No. 1147108-99-3
Cat. No. CS-W006079
Purity ≥98%
MDL No. MFCD11506701
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₂ClNO
Molecular Weight 137.61
Synonym(s) (S)-2-METHYLMORPHOLINE HYDROCHLORIDE（WS200397）
SMILES C[C@H]1CNCCO1.[H]Cl

Computational Chemistry Data

TPSA 21.26
LogP 0.4165
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(S)-2-Methylmorpholine hydrochloride

CAS No. 1147108-99-3

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