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CS-W001157 4
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(R)-2-(2-(tert-Butoxy)-2-oxoethyl)pentanoic acid

  • CAS No. 112106-16-8

  • Cat. No. CS-0102863
  • Molecule weight216.27
  • Purity≥95%
  • MDL No.MFCD30530776

*For research and further manufacturing use only, not for direct human use.

(R)-2-(2-(tert-Butoxy)-2-oxoethyl)pentanoic acid|CS-0102863

Structure of 112106-16-8

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General Information

  • CAS No. 112106-16-8
  • Cat. No. CS-0102863
  • Purity ≥95%
  • MDL No. MFCD30530776
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₀O₄
  • Molecular Weight 216.27
  • Synonym(s) (R)-2-(2-(tert-butoxy)-2-oxoethyl)pentanoic acid(BR30)
  • SMILES O=C(O)[C@H](CCC)CC(OC(C)(C)C)=O

Description

This chiral β-keto acid features a tert-butoxy carbonyl group flanking a stereogenic center, enabling selective functionalization in asymmetric synthesis. The pendant pentanoic acid chain provides a handle for derivatization, while the bench-stable, moisture-tolerant structure simplifies handling under standard conditions.

Application

(R)-2-(2-(tert-Butoxy)-2-oxoethyl)pentanoic acid serves as a versatile chiral building block for synthesizing bioactive molecules, leveraging its pendant ketone and carboxylic acid functionalities. The tert-butoxycarbonyl group enables protection of the α-amino moiety in subsequent transformations, while the stereogenic center ensures enantioselective outcomes in peptide-like scaffold construction. Its bench-stable nature and compatibility with standard coupling and reduction protocols facilitate efficient access to complex intermediates in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   63.6
  • LogP   2.2191
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   5

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