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N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-trityl-L-homoserine

  • CAS No. 111061-55-3

  • Cat. No. CS-0100960
  • Purity≥97%
  • MDL No.MFCD00270544

*For research and further manufacturing use only, not for direct human use.

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-trityl-L-homoserine|CS-0100960

Structure of 111061-55-3

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General Information

  • CAS No. 111061-55-3
  • Cat. No. CS-0100960
  • Purity ≥97%
  • MDL No. MFCD00270544
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₈H₃₃NO₅
  • Molecular Weight 583.67
  • Synonym(s) None
  • SMILES O=C(O)[C@H](CCOC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)NC(OCC4C5=C(C6=C4C=CC=C6)C=CC=C5)=O

Description

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-trityl-L-homoserine is a protected amino acid derivative designed for solid-phase peptide synthesis. The fluorenylmethoxycarbonyl (Fmoc) group enables orthogonal deprotection, while the trityl moiety provides robust protection of the hydroxyl side chain. This combination ensures high fidelity in sequence assembly and minimizes side reactions during coupling steps.

Synthesis

  • Route1
    • null|null
      28920-43-6
    • null|null
      111061-53-1
    • ~66%
    • In-stock
      N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-trityl-L-homoserine|CS-0100960
      111061-55-3

    References

    • Barlos, Kleomenis; Mamos, Petros; Papaioannou, Dionysios; Patrianakou, Stella; Sanida, Chariklia; Schaefer, Wolfram Liebigs Annalen der Chemie, 1987 , p. 1025 - 1030

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   84.86
  • LogP   7.3771
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   11

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