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tert-Butyl 3-hydroxymorpholine-4-carboxylate

  • CAS No. 1097871-14-1

  • Cat. No. CS-0099239
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 3-hydroxymorpholine-4-carboxylate|CS-0099239

Structure of 1097871-14-1

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General Information

  • CAS No. 1097871-14-1
  • Cat. No. CS-0099239
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₇NO₄
  • Molecular Weight 203.24
  • Synonym(s) None
  • SMILES O=C(N1C(O)COCC1)OC(C)(C)C

Description

tert-Butyl 3-hydroxymorpholine-4-carboxylate features a hydroxylated morpholine core with a tert-butyl ester handle, offering enhanced stability and solubility in organic media. This scaffold integrates readily into complex molecular architectures, serving as a key intermediate in the synthesis of bioactive heterocycles and pharmaceutical candidates.

Application

tert-Butyl 3-hydroxymorpholine-4-carboxylate serves as a versatile scaffold for morpholine-based heterocycles, enabling efficient access to bioactive molecules through selective transformations at the C3 hydroxyl and C4 carboxylate sites. Its tert-butyl ester facilitates mild deprotection, while the hydroxyl group supports orthogonal functionalization, enhancing utility in medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   59
  • LogP   0.5721
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   0

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