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Structure of 913642-78-1
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tert-Butyl 2-(2-hydroxyethyl)morpholine-4-carboxylate is a bench-stable, moisture-tolerant morpholine derivative featuring a pendant hydroxyl group and a protected carboxylic acid. This combination enables seamless integration into synthetic sequences requiring both nucleophilic versatility and selective deprotection pathways. The tert-butyl ester facilitates purification and handling, while the hydroxyethyl side chain supports downstream functionalization through etherification or oxidation.
tert-Butyl 2-(2-hydroxyethyl)morpholine-4-carboxylate serves as a versatile building block in medicinal chemistry, enabling efficient access to morpholine-containing scaffolds. The pendant hydroxyl group facilitates downstream derivatization via etherification or esterification, while the tert-butoxycarbonyl (Boc) group provides orthogonal protection for amine functionalization. Its bench-stable nature and compatibility with standard coupling conditions make it well-suited for multi-step synthesis and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: