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CS-W001157 4
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Boc-NH-PEG6-amine

  • CAS No. 1091627-77-8

  • Cat. No. CS-0115431
  • Purity≥97%
  • MDL No.MFCD16619391

*For research and further manufacturing use only, not for direct human use.

Boc-NH-PEG6-amine|CS-0115431

Structure of 1091627-77-8

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General Information

  • CAS No. 1091627-77-8
  • Cat. No. CS-0115431
  • Purity ≥97%
  • MDL No. MFCD16619391
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₄₀N₂O₈
  • Molecular Weight 424.53
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCCOCCOCCOCCOCCOCCOCCN

Description

Boc-NH-PEG6-amine features a tert-butoxycarbonyl-protected amine terminus on a six-ethylene glycol unit spacer, enabling stable conjugation in peptide and biomolecule labeling workflows. The PEG6 chain provides enhanced solubility and reduced non-specific binding, while the Boc group offers reliable protection during synthesis. This derivative streamlines site-specific modifications in bioconjugation applications.

Application

Boc-NH-PEG6-amine serves as a versatile, bench-stable linker for peptide and biomolecule conjugation. The tert-butoxycarbonyl (Boc) group provides orthogonal protection for primary amines, while the six-ethylene glycol (PEG6) spacer enhances solubility and reduces non-specific binding. This compound reacts efficiently with carboxylic acids under standard coupling conditions and functions as a key building block in the synthesis of PEGylated drug candidates, bioconjugates, and functionalized surfaces.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   119.73
  • LogP   0.5694
  • H_Acceptors   9
  • H_Donors   2
  • Rotatable_Bonds   20

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