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(S)-Octahydropyrazino[2,1-c][1,4]oxazine dihydrochloride

  • CAS No. 1089280-14-7

  • Cat. No. CS-0035562
  • Molecule weight215.12
  • Purity≥95%
  • MDL No.MFCD23105798

*For research and further manufacturing use only, not for direct human use.

(S)-Octahydropyrazino[2,1-c][1,4]oxazine dihydrochloride|CS-0035562

Structure of 1089280-14-7

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General Information

  • CAS No. 1089280-14-7
  • Cat. No. CS-0035562
  • Purity ≥95%
  • MDL No. MFCD23105798
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₆Cl₂N₂O
  • Molecular Weight 215.12
  • Synonym(s) None
  • SMILES N12CCNC[C@H]1COCC2.Cl.Cl

Description

This chiral heterocyclic dihydrochloride delivers a rigid, electron-rich scaffold ideal for asymmetric synthesis. Featuring a fully saturated pyrazino-oxazine core, it serves as a strategic nitrogen-containing building block in medicinal chemistry and catalytic system development under standard conditions.

Application

(S)-Octahydropyrazino[2,1-c][1,4]oxazine dihydrochloride serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to complex nitrogen-containing heterocycles. Its rigid, saturated framework provides excellent stereocontrol in downstream transformations, while the dihydrochloride salt enhances solubility and stability for bench handling. Functions effectively in amine coupling, reductive amination, and cyclization reactions, facilitating rapid scaffold diversification in API development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   24.5
  • LogP   0.134
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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