Lot numbers can be found on the outside label of a product:
Benzyl (4-nitrophenyl) carbonate
-
CAS No. 13795-24-9
- Cat. No. CS-0156216
- Purity≥97%
- MDL No.MFCD00007323
*For research and further manufacturing use only, not for direct human use.
Structure of 13795-24-9
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 13795-24-9
- Cat. No. CS-0156216
- Purity ≥97%
- MDL No. MFCD00007323
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₄H₁₁NO₅
- Molecular Weight 273.24
- Synonym(s) Carbonic acid, 4-nitrophenyl phenylmethyl ester
- SMILES C1=CC=C(C=C1)COC(=O)OC2=CC=C(C=C2)[N+](=O)[O-]
Description
Benzyl (4-nitrophenyl) carbonate serves as a stable, bench-ready protecting group for alcohols and thiols, enabling selective deprotection under mild conditions. The electron-deficient para-nitro group enhances leaving group ability, while the benzyl moiety offers orthogonal cleavage options. This reagent integrates seamlessly into synthetic workflows requiring precise functional group management.
Application
Benzyl (4-nitrophenyl) carbonate serves as a stable, bench-ready carbonylating agent for hydroxyl and amine functional groups. It facilitates efficient O- and N-carbamylation under mild conditions, enabling rapid access to protected intermediates in peptide synthesis and medicinal chemistry workflows. The 4-nitrophenyl leaving group ensures high reactivity with nucleophiles while maintaining excellent shelf stability and ease of purification.
Synthesis
-
Route1
-
100-02-7 -
501-53-1
- ~97%
-
In-stock
13795-24-9
References
-
Tepe, Jetze J.; Madalengoitia, Jose S.; Slunt, Kelli M.; Werbovetz, Karl W.; Spoors, P. Grant; Macdonald, Timothy L. Journal of Medicinal Chemistry, 1996 , vol. 39, # 11 p. 2188 - 2196
-
-
References
-
Chemische Berichte, , vol. 99, p. 3914 - 3924
-
-
Route3
-
100-02-7
-
1885-14-9
- ~82%
-
In-stock
13795-24-9
References
-
Boykin, David W.; Rahmathullah, M. Syed; Tidwell, Richard R.; Hall, James E. Patent: US2002/19437 A1, 2002 ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 78.67
- LogP 3.3104
- H_Acceptors 5
- H_Donors 0
- Rotatable_Bonds 4
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Benzyl (4-nitrophenyl) carbonate sigmaBenzyl (4-nitrophenyl) carbonate manufacturerBenzyl (4-nitrophenyl) carbonate priceBenzyl (4-nitrophenyl) carbonate structureBenzyl (4-nitrophenyl) carbonate SDSbuy Benzyl (4-nitrophenyl) carbonateBenzyl (4-nitrophenyl) carbonate supplierBenzyl (4-nitrophenyl) carbonate usesBenzyl (4-nitrophenyl) carbonate molecular weightprice of Benzyl (4-nitrophenyl) carbonateBenzyl (4-nitrophenyl) carbonate chemical name formula of Benzyl (4-nitrophenyl) carbonate