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5-Bromo-3-methoxypicolinaldehyde

  • CAS No. 1087659-24-2

  • Cat. No. CS-0130770
  • Molecule weight216.03
  • Purity≥96%
  • MDL No.MFCD11857632

*For research and further manufacturing use only, not for direct human use.

5-Bromo-3-methoxypicolinaldehyde|CS-0130770

Structure of 1087659-24-2

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General Information

  • CAS No. 1087659-24-2
  • Cat. No. CS-0130770
  • Purity ≥96%
  • MDL No. MFCD11857632
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrNO₂
  • Molecular Weight 216.03
  • Synonym(s) 5-bromo-3-methoxypyridine-2-carbaldehyde
  • SMILES O=CC1=NC=C(Br)C=C1OC

Description

5-Bromo-3-methoxypicolinaldehyde features a brominated pyridine core with complementary aldehyde and methoxy functionalities. This electron-deficient heterocycle integrates readily into cross-coupling reactions, serving as a key building block for bioactive scaffolds and functional materials under standard conditions.

Application

5-Bromo-3-methoxypicolinaldehyde serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its bromo and aldehyde functionalities. The methoxy group enhances solubility and modulates electronic effects, while the aldehyde facilitates imine formation and further functionalization. Its bench-stable nature and compatibility with standard reaction conditions make it well-suited for constructing complex heterocyclic scaffolds and pharmaceutical intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   39.19
  • LogP   1.6652
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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