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CS-W001157 4
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Boc-5-amino-2-methoxybenzoic acid

  • CAS No. 1075242-43-1

  • Cat. No. CS-0207693
  • Purity≥96%
  • MDL No.MFCD04972601

*For research and further manufacturing use only, not for direct human use.

Boc-5-amino-2-methoxybenzoic acid|CS-0207693

Structure of 1075242-43-1

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General Information

  • CAS No. 1075242-43-1
  • Cat. No. CS-0207693
  • Purity ≥96%
  • MDL No. MFCD04972601
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₇NO₅
  • Molecular Weight 267.28
  • Synonym(s) 2-Methoxy-5-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
  • SMILES CC(C)(OC(NC1=CC(C(O)=O)=C(OC)C=C1)=O)C

Description

Boc-5-amino-2-methoxybenzoic acid features a protected amino group and a methoxy-substituted aromatic core, enabling direct incorporation into peptide chains or complex molecular scaffolds. This bench-stable derivative facilitates efficient coupling reactions under standard conditions, offering enhanced solubility in organic media while minimizing side reactivity.

Application

Boc-5-amino-2-methoxybenzoic acid serves as a versatile building block for the synthesis of bioactive heterocycles and peptide-conjugated scaffolds. The Boc group provides stable protection of the primary amine, enabling orthogonal handling in multi-step syntheses. The ortho-methoxy substituent enhances electron donation and modulates reactivity in subsequent coupling or cyclization reactions. This compound facilitates efficient access to substituted benzimidazoles, benzoxazoles, and related pharmacophores under standard synthetic conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   84.86
  • LogP   2.7404
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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