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CS-W001157 4
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2-Phenyloxazole-5-carboxylic acid

  • CAS No. 106833-79-8

  • Cat. No. CS-W006692
  • Purity≥95%
  • MDL No.MFCD08361772

*For research and further manufacturing use only, not for direct human use.

2-Phenyloxazole-5-carboxylic acid|CS-W006692

Structure of 106833-79-8

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General Information

  • CAS No. 106833-79-8
  • Cat. No. CS-W006692
  • Purity ≥95%
  • MDL No. MFCD08361772
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₇NO₃
  • Molecular Weight 189.17
  • Synonym(s) Ec-000.1791
  • SMILES C1=C(OC(=N1)C2=CC=CC=C2)C(=O)O

Description

2-Phenyloxazole-5-carboxylic acid features a rigid oxazole core fused with a phenyl ring and a carboxylic acid group at the 5-position, delivering enhanced stability and polarity. This structural motif enables direct integration into bioactive scaffolds, offering favorable solubility and compatibility in medicinal chemistry campaigns.

Application

2-Phenyloxazole-5-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its ortho-functionalized oxazole core enables reliable coupling reactions, while the carboxylic acid group facilitates derivatization via amide, ester, or amidation protocols. The molecule exhibits good bench stability and clean purification profiles, making it well-suited for iterative synthesis workflows and API scaffold development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.33
  • LogP   2.0398
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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