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CS-W001157 4
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(S)-N,N-Dimethylpiperidin-3-amine hydrochloride

  • CAS No. 1061682-82-3

  • Cat. No. CS-0196482
  • Purity≥97%
  • MDL No.MFCD20687658
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

(S)-N,N-Dimethylpiperidin-3-amine hydrochloride|CS-0196482

Structure of 1061682-82-3

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Description

(S)-N,N-Dimethylpiperidin-3-amine hydrochloride is a chiral amine scaffold featuring a sterically hindered tertiary nitrogen and a protonated piperidine ring under standard conditions. This bench-stable salt delivers enhanced solubility in aqueous and polar organic media, enabling efficient incorporation into catalytic systems and synthetic intermediates.

Application

(S)-N,N-Dimethylpiperidin-3-amine hydrochloride serves as a versatile chiral building block in medicinal chemistry, enabling the construction of bioactive heterocycles and pharmaceutical scaffolds. Its tertiary amine functionality offers favorable basicity and solubility, while the piperidine core provides conformational rigidity beneficial for target binding. The hydrochloride salt enhances bench stability and simplifies purification, facilitating its use in standard coupling reactions, reductive amination, and parallel synthesis workflows.

General Information

  • CAS No. 1061682-82-3
  • Cat. No. CS-0196482
  • Purity ≥97%
  • MDL No. MFCD20687658
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₇ClN₂
  • Molecular Weight 164.68
  • Synonym(s) None
  • SMILES CN(C)[C@H]1CCCNC1.Cl

Computational Chemistry Data

  • TPSA   15.27
  • LogP   0.7218
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3259
Class : 8
Packing Group :
Hazard Statements : H314-H318
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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