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CS-W001157 4
Total: USD 88.00

1-Cyclopentylethanone

  • CAS No. 6004-60-0

  • Cat. No. CS-W020214
  • Purity≥96%
  • MDL No.MFCD00060799

*For research and further manufacturing use only, not for direct human use.

1-Cyclopentylethanone|CS-W020214

Structure of 6004-60-0

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General Information

  • CAS No. 6004-60-0
  • Cat. No. CS-W020214
  • Purity ≥96%
  • MDL No. MFCD00060799
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₂O
  • Molecular Weight 112.17
  • Synonym(s) Cyclopentylethanone
  • SMILES CC(C1CCCC1)=O

Description

1-Cyclopentylethanone is a cyclic ketone featuring a cyclopentyl ring directly bonded to an acetyl group. This structure combines ring strain with a reactive carbonyl, enabling its use in nucleophilic additions and as a building block for complex organic frameworks. The molecule exhibits good stability under standard conditions and facilitates efficient functionalization in synthetic pathways.

Application

1-Cyclopentylethanone serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized cyclopentane derivatives. Its ketone functionality facilitates nucleophilic additions, enolate formation, and conjugate additions, while the adjacent cyclopentyl ring provides structural rigidity beneficial for stereocontrolled synthesis. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for iterative transformations in medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • null|null
      917-54-4
    • N-Methoxy-N-methylcyclopentanecarboxamide|CS-0123030
      167303-65-3
    • ~74%
    • In-stock
      1-Cyclopentylethanone|CS-W020214
      6004-60-0

    References

    • Chapal, Nicolas; McNicol, Patricia; Jette, Lucie Patent: US2006/223884 A1, 2006 ; Location in patent: Page/Page column 56 ;
  • Route2
    • null|null
      138837-21-5
    • ~89%
    • In-stock
      1-Cyclopentylethanone|CS-W020214
      6004-60-0

    References

    • ACTELION PHARMACEUTICALS LTD; SCHMIDT, Gunther Patent: WO2013/175397 A1, 2013 ; Location in patent: Page/Page column 22 ;
  • Route3

    References

    • Annales de Chimie (Cachan, France), , vol. <11> 4, p. 5,48 Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 198, p. 2254,2255

Safety Information

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GHS Pictogram :
GHS No : GHS02
Signal Word : Danger
UN#: 1224
Class : 3
Packing Group : Ⅱ
Hazard Statements : H225
Precautionary Statements : P210-P233-P370+P378-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   1.7656
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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