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(S)-N,N-Dimethylpiperidin-3-amine hydrochloride

  • CAS No. 1061682-82-3

  • Cat. No. CS-0196482
  • Purity≥97%
  • MDL No.MFCD20687658

*For research and further manufacturing use only, not for direct human use.

(S)-N,N-Dimethylpiperidin-3-amine hydrochloride|CS-0196482

Structure of 1061682-82-3

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General Information

  • CAS No. 1061682-82-3
  • Cat. No. CS-0196482
  • Purity ≥97%
  • MDL No. MFCD20687658
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₇ClN₂
  • Molecular Weight 164.68
  • Synonym(s) None
  • SMILES CN(C)[C@H]1CCCNC1.Cl

Description

(S)-N,N-Dimethylpiperidin-3-amine hydrochloride is a chiral amine scaffold featuring a sterically hindered tertiary nitrogen and a protonated piperidine ring under standard conditions. This bench-stable salt delivers enhanced solubility in aqueous and polar organic media, enabling efficient incorporation into catalytic systems and synthetic intermediates.

Application

(S)-N,N-Dimethylpiperidin-3-amine hydrochloride serves as a versatile chiral building block in medicinal chemistry, enabling the construction of bioactive heterocycles and pharmaceutical scaffolds. Its tertiary amine functionality offers favorable basicity and solubility, while the piperidine core provides conformational rigidity beneficial for target binding. The hydrochloride salt enhances bench stability and simplifies purification, facilitating its use in standard coupling reactions, reductive amination, and parallel synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3259
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314-H318
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   15.27
  • LogP   0.7218
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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