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CS-W001157 4
Total: USD 88.00

5-Bromopyrazolo[1,5-a]pyridine

  • CAS No. 1060812-84-1

  • Cat. No. CS-W020187
  • Purity≥96%
  • MDL No.MFCD13189494

*For research and further manufacturing use only, not for direct human use.

5-Bromopyrazolo[1,5-a]pyridine|CS-W020187

Structure of 1060812-84-1

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General Information

  • CAS No. 1060812-84-1
  • Cat. No. CS-W020187
  • Purity ≥96%
  • MDL No. MFCD13189494
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅BrN₂
  • Molecular Weight 197.03
  • Synonym(s) 5-Bromopyrazolo[1,5-a]pyridine(1060812-84-1)
  • SMILES BrC1=CC2=CC=NN2C=C1

Description

5-Bromopyrazolo[1,5-a]pyridine is a heterocyclic building block featuring a brominated pyrazolopyridine core. This electron-deficient scaffold enables direct functionalization in cross-coupling reactions and serves as a key intermediate in the synthesis of bioactive molecules. The bromine substituent facilitates palladium-catalyzed transformations with high efficiency under standard conditions.

Application

5-Bromopyrazolo[1,5-a]pyridine serves as a versatile building block for the synthesis of functionalized heterocycles and pharmaceutical intermediates. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, facilitating the construction of biaryl and extended π-conjugated systems. The molecule exhibits good bench stability and compatibility with common protecting groups, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.

Safety Information

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Computational Chemistry Data

  • TPSA   17.3
  • LogP   2.0968
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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