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CS-W001157 4
Total: USD 88.00

6-Bromopyrazolo[1,5-a]pyridine

  • CAS No. 1264193-11-4

  • Cat. No. CS-W006121
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-Bromopyrazolo[1,5-a]pyridine|CS-W006121

Structure of 1264193-11-4

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General Information

  • CAS No. 1264193-11-4
  • Cat. No. CS-W006121
  • Purity ≥96%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅BrN₂
  • Molecular Weight 197.03
  • Synonym(s) None
  • SMILES BrC1=CN2N=CC=C2C=C1

Description

6-Bromopyrazolo[1,5-a]pyridine features a bromine substituent at the 6-position of a fused pyrazolo[1,5-a]pyridine core, providing a reactive handle for palladium-catalyzed cross-coupling transformations. The electron-deficient heteroaromatic framework enables efficient incorporation into bioactive scaffolds and functional materials. This bench-stable compound serves as a key intermediate in synthetic medicinal chemistry and advanced materials development.

Application

6-Bromopyrazolo[1,5-a]pyridine serves as a versatile building block for the synthesis of heterocyclic scaffolds in medicinal chemistry and catalytic cross-coupling reactions. The bromine substituent enables reliable Suzuki, Stille, or Buchwald–Hartwig coupling transformations, facilitating the construction of biaryl and complex nitrogen-containing frameworks. Its stability under standard reaction conditions and compatibility with diverse functional groups make it a practical choice for iterative synthesis and library generation.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.3
  • LogP   2.0968
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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