Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Chloro-5-iodopyrazine

  • CAS No. 1057216-55-3

  • Cat. No. CS-0018826
  • Purity≥97%
  • MDL No.MFCD09909701

*For research and further manufacturing use only, not for direct human use.

2-Chloro-5-iodopyrazine|CS-0018826

Structure of 1057216-55-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1057216-55-3
  • Cat. No. CS-0018826
  • Purity ≥97%
  • MDL No. MFCD09909701
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₂ClIN₂
  • Molecular Weight 240.43
  • Synonym(s) 2-Chloro-5-iodo-pyrazine
  • SMILES IC1=CN=C(Cl)C=N1

Description

2-Chloro-5-iodopyrazine is a halogenated pyrazine derivative featuring complementary reactive sites for cross-coupling. The chlorine and iodine substituents enable sequential functionalization under palladium-catalyzed conditions, facilitating rapid diversification in heterocyclic synthesis. This electron-deficient scaffold integrates efficiently into complex molecular architectures with high chemoselectivity.

Application

2-Chloro-5-iodopyrazine serves as a versatile heterocyclic building block for palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and functionalized pyrazine scaffolds. The ortho-chloro and iodo substituents offer complementary reactivity profiles, allowing sequential functionalization with high chemoselectivity. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for iterative synthesis in medicinal chemistry and materials development.

Synthesis

  • Route1

    References

    • US2005/234046 A1, ; Page/Page column 70 ; US 20050234046 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   25.78
  • LogP   1.7346
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Chloro-5-iodopyrazine sigma2-Chloro-5-iodopyrazine manufacturer2-Chloro-5-iodopyrazine price2-Chloro-5-iodopyrazine structure2-Chloro-5-iodopyrazine SDSbuy 2-Chloro-5-iodopyrazine2-Chloro-5-iodopyrazine supplier2-Chloro-5-iodopyrazine uses2-Chloro-5-iodopyrazine molecular weightprice of 2-Chloro-5-iodopyrazine2-Chloro-5-iodopyrazine chemical name formula of 2-Chloro-5-iodopyrazine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label