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CS-W001157 4
Total: USD 88.00

(2-Oxoindolin-5-yl)boronic acid

  • CAS No. 1051316-38-1

  • Cat. No. CS-0054245
  • Purity≥95%
  • MDL No.MFCD10696667

*For research and further manufacturing use only, not for direct human use.

(2-Oxoindolin-5-yl)boronic acid|CS-0054245

Structure of 1051316-38-1

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General Information

  • CAS No. 1051316-38-1
  • Cat. No. CS-0054245
  • Purity ≥95%
  • MDL No. MFCD10696667
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈BNO₃
  • Molecular Weight 176.97
  • Synonym(s) Oxindole-5-boronic acid
  • SMILES O=C1NC2=C(C=C(B(O)O)C=C2)C1

Description

This boronate moiety integrates seamlessly into Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under standard conditions. The electron-deficient indolinone scaffold enhances reactivity while maintaining bench-stable handling characteristics.

Application

(2-Oxoindolin-5-yl)boronic acid serves as a versatile building block for Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biologically relevant indoline derivatives. Its stability under ambient conditions and compatibility with diverse functional groups facilitate straightforward incorporation into complex molecular architectures. The boronic acid moiety enables reliable coupling with aryl and heteroaryl halides, making it a practical reagent for medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   69.56
  • LogP   -1.139
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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