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Structure of 1040377-02-3
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4-Bromo-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole features a brominated pyrazole core linked to a tetrahydropyran handle, enabling direct integration into diversification workflows. This bench-stable scaffold offers enhanced solubility and compatibility in transition-metal-catalyzed coupling reactions.
4-Bromo-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo functionality. The tetrahydro-2H-pyran-4-yl group provides excellent solubility and bench stability, while the pyrazole core offers predictable reactivity in heterocyclic synthesis. This compound facilitates efficient access to complex scaffolds via standard coupling protocols and is well-suited for iterative functionalization in drug discovery campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: