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CS-W001157 4
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(R)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methanamine

  • CAS No. 103883-30-3

  • Cat. No. CS-W005528
  • Purity≥97%
  • MDL No.MFCD02262087

*For research and further manufacturing use only, not for direct human use.

(R)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methanamine|CS-W005528

Structure of 103883-30-3

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General Information

  • CAS No. 103883-30-3
  • Cat. No. CS-W005528
  • Purity ≥97%
  • MDL No. MFCD02262087
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₃NO₂
  • Molecular Weight None
  • Synonym(s) None
  • SMILES NC[C@H]1OC(C)(C)OC1

Description

(R)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methanamine is a chiral building block featuring a stable dioxolane ring with a primary amine handle. The stereogenic center at the 4-position imparts enantioselective utility in asymmetric synthesis. This bench-stable derivative integrates readily into peptide and nucleoside analogs, offering controlled reactivity under standard conditions.

Application

(R)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methanamine serves as a stable, bench-ready chiral building block for the synthesis of nucleoside analogs and bioactive heterocycles. Its protected hydroxyl groups enable orthogonal functionalization, while the primary amine facilitates coupling reactions under mild conditions. The molecule’s inherent stereochemical integrity and resistance to racemization make it ideal for asymmetric synthesis workflows in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS05,GHS07
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H314-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P271-P280-P303+P361+P353-P304+P340-P312-P370+P378-P403+P233-P403+P235-P405-P501

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Computational Chemistry Data

  • TPSA   44.48
  • LogP   0.0966
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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