(2,2-Dimethyl-1,3-dioxolan-4-yl)methanamine hydrochloride

Name: (2,2-Dimethyl-1,3-dioxolan-4-yl)methanamine hydrochloride
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CAS No. 167301-82-8
Cat. No. CS-0043805
Purity≥95%
MDL No.MFCD22375314

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(2,2-Dimethyl-1,3-dioxolan-4-yl)methanamine hydrochloride|CS-0043805

Structure of 167301-82-8

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General Information

CAS No. 167301-82-8
Cat. No. CS-0043805
Purity ≥95%
MDL No. MFCD22375314
Storage 4°C, stored under nitrogen, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₄ClNO₂
Molecular Weight 167.63
Synonym(s) (2,2-dimethyl-1,3-dioxolan-4- yl)methanamine hydrochloride
SMILES NCC1OC(C)(C)OC1.[H]Cl

Description

This bench-stable, moisture-tolerant amine derivative features a protected diamine scaffold ideal for controlled functionalization in synthetic workflows. The hydrochloride salt enhances solubility and handling, enabling efficient incorporation into peptide couplings and bioconjugation strategies under standard conditions.

Application

(2,2-Dimethyl-1,3-dioxolan-4-yl)methanamine hydrochloride serves as a stable, bench-ready building block for the synthesis of amino-functionalized heterocycles. Its protected amine functionality enables selective deprotection and coupling reactions under mild conditions, facilitating access to diverse scaffolds in medicinal chemistry. The dioxolane ring enhances solubility and stability, while the hydrochloride salt form ensures ease of handling and purification in standard synthetic workflows.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 44.48
LogP 0.5184
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Dioxolane compounds

Key Words

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(2,2-Dimethyl-1,3-dioxolan-4-yl)methanamine hydrochloride

CAS No. 167301-82-8

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