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Structure of 1036990-42-7
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2-(Trifluoromethyl)pyridine-4-boronic acid pinacol ester features a trifluoromethyl group at the ortho position, enhancing electronic withdrawal and metabolic stability. The pinacol boronate moiety enables reliable Suzuki-Miyaura coupling under standard conditions, offering robustness in cross-coupling reactions with aryl halides. This bench-stable reagent integrates efficiently into complex molecular architectures requiring electron-deficient pyridine motifs.
2-(Trifluoromethyl)pyridine-4-boronic acid pinacol ester serves as a stable, bench-ready building block for Suzuki-Miyaura cross-coupling reactions. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the pyridine core provides a versatile heterocyclic scaffold. Its boronic ester functionality enables reliable coupling with aryl and heteroaryl halides under mild conditions, offering high functional group tolerance and ease of purification—ideal for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: