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Structure of 1218790-39-6
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5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine features a boronate ester group paired with a strongly electron-withdrawing trifluoromethyl pyridine scaffold. This combination enables efficient Suzuki-Miyaura cross-coupling under mild conditions, offering excellent functional group tolerance and stability during storage and handling.
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)pyridine serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the sterically protected boronate ester ensures excellent shelf life and functional group tolerance. This reagent facilitates efficient C–C bond formation under mild conditions, enabling rapid access to complex pyridine-based scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: