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CS-W001157 4
Total: USD 88.00

(3R)-1,3-Dimethylpiperazine

  • CAS No. 1033717-21-3

  • Cat. No. CS-0006865
  • Purity≥97%
  • MDL No.MFCD11114439

*For research and further manufacturing use only, not for direct human use.

(3R)-1,3-Dimethylpiperazine|CS-0006865

Structure of 1033717-21-3

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General Information

  • CAS No. 1033717-21-3
  • Cat. No. CS-0006865
  • Purity ≥97%
  • MDL No. MFCD11114439
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₄N₂
  • Molecular Weight 114.19
  • Synonym(s) (R)-1,3-Dimethylpiperazine
  • SMILES C[C@@H]1CN(C)CCN1

Description

This chiral piperazine derivative features a defined (3R) stereochemistry, offering enhanced selectivity in asymmetric synthesis. The dimethyl substitution pattern imparts favorable solubility and stability under standard bench conditions, enabling reliable use in medicinal chemistry and catalyst design.

Application

(3R)-1,3-Dimethylpiperazine serves as a chiral building block in medicinal chemistry, offering a rigid, sterically defined scaffold with enhanced solubility and metabolic stability. Its tertiary amine functionality facilitates salt formation and hydrogen bonding, while the (3R) stereochemistry enables predictable conformational control in target-directed synthesis. The compound exhibits bench stability and compatibility with standard coupling and functionalization protocols, making it well-suited for parallel library construction and API development.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS05,GHS06
Signal Word : Danger
UN#: 2734
Class : 8 (3)
Packing Group : Ⅱ
Hazard Statements : H225-H312-H314-H331
Precautionary Statements : P210-P240-P241-P280-P370+P378

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Computational Chemistry Data

  • TPSA   15.27
  • LogP   -0.0901
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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