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CS-W001157 4
Total: USD 88.00

(S)-1,3-Dimethylpiperazine

  • CAS No. 1152367-80-0

  • Cat. No. CS-0054951
  • Purity≥95%
  • MDL No.MFCD11114436

*For research and further manufacturing use only, not for direct human use.

(S)-1,3-Dimethylpiperazine|CS-0054951

Structure of 1152367-80-0

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General Information

  • CAS No. 1152367-80-0
  • Cat. No. CS-0054951
  • Purity ≥95%
  • MDL No. MFCD11114436
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₄N₂
  • Molecular Weight None
  • Synonym(s) (3S)-1,3-diMethylpiperazine
  • SMILES C[C@H]1CN(C)CCN1

Description

(S)-1,3-Dimethylpiperazine is a chiral piperazine derivative featuring two methyl groups at the 1- and 3-positions, conferring enhanced steric bulk and improved solubility in organic media. This configuration imparts distinct stereochemical properties useful in asymmetric synthesis and medicinal chemistry applications, where controlled spatial orientation influences binding affinity and metabolic stability.

Application

(S)-1,3-Dimethylpiperazine serves as a versatile chiral building block in medicinal chemistry, enabling the construction of bioactive heterocycles with defined stereochemistry. Its tertiary amine functionality offers favorable solubility and basicity, while the piperazine core provides metabolic stability and hydrogen-bonding capacity. The compound exhibits excellent bench stability and compatibility with standard coupling reactions, facilitating efficient incorporation into API scaffolds and complex molecular architectures.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   15.27
  • LogP   -0.0901
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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